Before there was a church here there was a 3rd century Paleo-Christian cemetery, the final resting places of the Martyrs Sisinio, Martirio and Alessandro. St. Ambrose built one of his four churches on this location, making it one of the oldest churches in the city. The church became famous in the 11th century, when the martyrs buried here supposedly gave their forms to doves, landing on the city's Carroccio, (a ceremonial war waggon), as a symbol of courage to the Lombard League against their battle with Frederick Barbarossa. The current Romanesque look was created during the 12th and 13th centuries. See the mullioned windows. The side chapels contain art from various periods - Renaissance, Baroque, Rococo, and Neoclassical. The stained glass windows depict the battle of Legnano.

• Trams 2, 4, 12, 14 stop Lanza m2
• Subway M2 stop Lanza
• Bus 61 stop Lanza m2
• Bus 57 stop Acquario Civico
• Bus 43, 94 stop Acquario Civico

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