Home to pretty treasures, Misilmeri is Italy's best kept secret. The nearest major city to Misilmeri is Catania. Catania is bestowed with interesting set of attractions like Caltagirone, Mount Etna, Piazza Duomo. Also, to reach Misilmeri, you'll have to take a flight to Catania; so its not really a detour. And even if it is, the city is worth paying at least a quick visit. 1-2 days is an ideal duration of visit to Misilmeri.
Don't just take a trip, let the trip take you! Have a enjoyable time at Misilmeri.