Looking for travel information about Spiro? Explore the best travel advice on Spiro, United States. Spiro is located at a short trip away from Muskogee a major city in United States. Muskogee is bestowed with interesting set of attractions for every type of traveller. To reach Spiro, hop on a flight to airport which is the nearest major Muskogee Regional Medical Center Heliport. Tour packages of Spiro are of 1 to 2 days duration.