Planning a vacation to St Charles in United States? This vacation planner will provide you with all the essential information you need. The nearest major city to St Charles is Saint Louis. Saint Louis is bestowed with interesting set of attractions like Gateway Arch, Saint Louis Zoo, City Museum. Also, to reach St Charles, you'll have to take a flight to Saint Louis; so its not really a detour. And even if it is, the city is worth paying at least a quick visit. Most online packages to this city are of 1-2 days.