After a pickup from your central Rome hotel, travel north with your guide. Pass the green valley that surrounds the River Tiber, and head across the gentle foothills of the Apennines to reach Tuscany.
Your first stop in the region is Pisa, home to the gleaming white monuments of Piazza dei Miracoli. The most famous is the Leaning Tower of Pisa, an iconic UNESCO site, which is recognised around the world. Pose for photos outside the tower and see Pisa Baptistery and Pisa Duomo.
Continue to Florence for lunch (own expense), and then meet back with your guide for a tour of the center. Work your way around medieval streets, see old craftsmen workshops, and learn about the powerful Medici family who became de facto rulers of the city.
Next, visit the Accademia Gallery to see influential artwork by the Renaissance greats: Michelangelo, Da Vinci and Botticelli. Admire Michelangelos David, and then head outside to explore Florences centro storico.
See Florence Duomo and Brunelleschis Dome, admire Florence Baptistery, and gaze up at Giottos Bell Tower. Finish with a trip up to the vantage point of Piazzale Michelangelo for panoramic views of Ponte Vecchio, River Arno, and Florence Duomo.
Relax on the journey back to Rome, and finish your day with a hotel drop-off.